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Evidence and Research Comparison# Semaglutide Research# Semaglutide has one of the most extensive clinical evidence bases of any peptide therapeutic: SUSTAIN trials : Seven Phase 3 studies in type 2 diabetes demonstrating HbA1c reduction and weight loss STEP trials : Four Phase 3 studies in obesity

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A realistic timeline may look like: First 48 weeks: early changes in energy, sleep, recovery, or body composition may be noticed by some clients 812 weeks: more meaningful body-composition changes may begin to appear 36 months: better window for evaluating abdominal-fat and body-composition response 6+ months: longer protocols may be considered depending on provider guidance Actual results vary based on body composition, nutrition, exercise, sleep, hormones, metabolic health, and consistency